Mild side effects of Femara can usually go away within a few days or a couple weeks. Examples of both mild and serious side effects that can occur when using Femara for infertility include: Youll usually take Femara by mouth once daily for 5 days after the start of your menstrual cycle. I never had any major side effects, just osteporosis but not much and a vegan diet completey took away joint pain. Learn the signs and symptoms of metastasis, how you can make yourself as comfortable as possible, and tips for managing end-of-life symptoms. Spotting may occur along with other side effects from Femara, such as belly pain or cramping. As with most drugs, some people can have an allergic reaction after taking Femara. Most doctors wont prescribe Femara for more than six cycles of treatment. When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Like most drugs, Femara can cause an allergic reaction in some people. Most people are given letrozole for 5 years, but some will take it for up to 10 years. Mild side effects of many . Learn about the dosage for Femara in treating certain types of breast cancer. swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dosage of the drug you were taking when you had the side effect, how soon after starting that dosage you experienced it, any other medications you were also taking, any other information you feel is important. * For more information on this side effect, see the Side effect focus section below. They can recommend healthy ways for you to manage your weight. Below are lists of medications that can interact with Femara. Allergic reaction. The recommended length of time that letrozole is taken for will depend on your individual situation. Your doctor or pharmacist can tell you about any interactions these items may cause with Femara. Other drugs are available that can treat breast cancer. Visit Medicine Assistance Tool to find programs that may help lower your cost of Femara. This means that chemotherapy can affect both cancer cells and healthy cells. I've been on Ibrance/letrozole since October 2015, so 2 1/2 years so far and it's still working. And talk with your doctor about ways to help improve your energy level during treatment. When talking with your doctor, you may want to ask the following questions: To learn more about breast cancer and its treatment options, sign up for Healthlines breast cancer newsletter. What are the serious side effects of Femara? Alcohol isnt known to interact with Femara. But some healthy cells in the body also quickly multiply. For information about the difference between sex and gender, see this article. Femara can weaken your bones, which may cause new or worsened osteoporosis. When used for this purpose, Femara helps lower the risk of your cancer coming back. It only has these risks if its taken when youre already pregnant. During clinical studies, both weight gain and weight loss were reported in people who took Femara for breast cancer treatment. * Sex and gender exist on spectrums. If you drink alcohol and youre concerned about how this might affect your condition, talk with your doctor. If you find the side effects ease within the two weeks they may try you on Anastrozole or even Exemstane. Ovulation tends to occur between 5 and 10 days after youve taken your last Femara tablet. Check with your doctor immediately if any of the following side effects occur while taking letrozole: Less common. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. For this use, youll take Femara for a few days after the start of your period. Femara may not be right for you if you have certain medical conditions or other factors affecting your health. The insurance company will review the request and let you and your doctor know if your plan will cover Femara. In other words, it takes about 2 days for your body to get rid of half of a Femara dose. Side effects usually improve after a few months as your body gets used to the medicine. PCOS is a condition that causes hormone problems, irregular or skipped periods, and cysts on your ovaries. (A drug class is a group of medications that work in a similar way.). What can I do to help prevent the aches and pains that Ive heard are a side effect of taking Femara? Our website services, content, and products are for informational purposes only. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. What happens when you stop taking letrozole? But this was not one of the most common side effects reported in studies of the drug. (With off-label use, a drug thats approved to treat one condition is used to treat another.). Find answers to some commonly asked questions about Femara. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Femara can stay in your system for several weeks after your last dose. What Types of Breast Cancer Have the Highest Recurrence Rates? It also helps keep the drug from harming the environment. This medicine is available only with your doctor's prescription. Bone fracture; breast pain; chest pain No, you likely wont. Healthline Media does not provide medical advice, diagnosis, or treatment. You should take Letrozole at about the same time each day. These hormones stimulate an egg in your ovary to mature and be released from your ovary. A medication timer may be useful, too. I was prescribed Letrozole about 6 weeks before my operation, bilateral mastectomy with implants. But if it contains estrogen, it may interact with Femara treatment. It works by lowering the amount of estrogen your body makes. hot flashes flushed skin increased sweating joint pain weakness edema (swelling), possibly in your ankles or feet headache dizziness bone pain The mild side effects of Femara that are less. When Femara is used off-label to treat infertility, the drug doesnt increase the risk of birth defects or miscarriage. This was common in clinical studies of the drug. If you have questions about Femaras success rate in treating cancer, talk with your doctor. These and other important considerations are discussed in more detail below. These lists dont include all possible side effects. If you miss a dose, do not take a double dose the next day. Plasma concentrations at steady state are 1.5 to 2 times higher than predicted from the concentrations measured after a single dose, indicating a slight non-linearity in the hormone therapies, other than Femara, such as: chemotherapy (traditional drugs used to treat cancer), such as: vaginal estrogen products, such as creams, tablets, suppositories, and rings, certain birth control medications, such as. But if you think youre having a medical emergency, call 911 or your local emergency number. They work by lowering estrogen levels within your body, which helps stop the growth of breast cancer. Over-the-counter (OTC) medications, such as acetaminophen (Tylenol) and ibuprofen (Advil), may be effective for relieving headaches. The Food and Drug Administration (FDA) approves prescription drugs such as Femara to treat certain conditions. Also tell them about any vitamins, herbs, and supplements you use. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Heres some detail on several of the side effects this drug cause. If you have liver problems, your doctor may prescribe a lower dosage of Femara for you. Femara isnt approved to treat infertility in males. My doctor said Femara may cause hot flashes. Dont take more Femara than your doctor prescribes. Clomid has been discontinued, but generic versions of clomiphene are still available. Serious side effects of Femara that have been reported include: Learn more about some of the side effects Femara may cause. But its not known if drinking alcohol after youre diagnosed with breast cancer can make your cancer worse or more likely to come back after treatment. As with all medications, the cost of Femara can vary. This helps prevent others, including children and pets, from taking the drug by accident. Its a prescription drug thats used to treat certain types of breast cancer in adult females* who have gone through menopause. Do not stop taking letrozole without talking to your treatment team first. Learn. Femara may cause fatigue (lack of energy) in some people. Tell them about all prescription, over-the-counter, and other drugs you take. Treatment will be taken over five consecutive days. Femara is a prescription drug used in adult females* whove gone through menopause. If youd like to know about using Femara for these purposes, talk with your doctor. Femara is also sometimes used off-label to treat infertility in females with endometriosis. Liver problems. Call your doctor if you think youve taken too much Femara. A medication timer may be useful, too. You should always consult your doctor or another healthcare professional before taking any medication. Breast cancer develops when cells in your breast tissue start to grow and multiply more quickly than usual. So researchers wanted to know if taking an aromatase inhibitor for 10 years would offer more benefits than taking one for 5 years. The mild side effects of Femara that are more common* can include: The mild side effects of Femara that are less common** can include: * Occurred in more than 20% of people in clinical studies ** Occurred in 20% or less of people in clinical studies. The usual dosage of Femara for breast cancer treatment is one tablet taken by mouth once each day. Call your doctor right away if you have bone pain. Your doctor may ask you to start taking the drug either on day 3 or day 5 of your menstrual cycle. Talk with your doctor about how long you should take Femara for adjuvant treatment of breast cancer. Over the last week I have been feeling increasingly poorly, very lethargic and completely lacking in energy as I have just come back from a lovely week away there really shouldn't be any reason for how I am feeling and it just occurred to me that it could be related to stopping taking tamoxifen. They can tell you about other medications that may work well for you. This product is available in the following dosage forms: Tablet You should not stop taking Letrozole without discussing with your physician. I had no radiotherapy or chemotherapy. Most of these side effects may go away within a few days or a couple of weeks. PCOS is a condition that causes hormone problems, irregular or skipped periods, and cysts on your ovaries. Hormone therapy may also be used to treat hot flashes. Below youll find answers to some frequently asked questions about Femaras side effects. Femara is used in the following ways to treat advanced breast cancer: Femara has been found to be effective in treating advanced breast cancer. Headaches were a common side effect in studies of Femara. reduced the number of deaths from breast cancer. If you do drink alcohol while taking Femara, you might be more likely to experience: If you plan to drink alcohol while taking Femara, talk with your doctor about how much may be safe for you to drink. And there are other drugs used to treat infertility that do other things in your body. These types of therapies stop estrogen from encouraging breast cancer cells to grow. 2005-2023 Healthline Media a Red Ventures Company. One way your doctor will monitor your bone strength is by measuring your bone mineral density. Be sure to always take Femara exactly as your doctor recommends. Generally it takes four to five half-lives for a drug to be eliminated from the body, so in the case of Arimidex this would be 150 to 300 hours, or six to 12 days. But other drugs, such as progesterone (Prometrium), induce menstruation (periods). The list below includes factors to consider. Learn about side effects, warnings, dosage. https://breastcancernow.org/information-support/facing-breast-cancer/going-through-breast-cancer-treatment/hormone-therapy/letrozole-femara. Letrozole lowers the levels of the female sex hormone oestrogen in the body. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. Withdrawal symptoms are side effects that can happen when you stop taking a drug that your body has become dependent on. Your doctor will also advise when you should start having sex if youre trying to conceive (TTC) naturally. In some cases, your doctor may prescribe Femara after youve taken tamoxifen for your cancer for at least 5 years. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Femara may be used off-label to treat infertility due to PCOS and other causes. What should be considered before taking Femara? The drugs work by lowering estrogen levels in your body, which helps stop breast cancer from growing. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Hormone therapies stop estrogen from encouraging breast cancer cells to grow. You should always consult your doctor or another healthcare professional before taking any medication. You can take Femara with or without food. Melatonin and Breast Cancer: Is it Safe and Can it Help? But try to take it around the same time on each of the 5 days that youre taking the drug. Your doctor will explain how you should take Femara, such as how much to take and how often. Before taking Femara, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. * For more information about using Femara for infertility, see the section Off-label use of Femara for infertility above. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. The highest dose of Femara for fertility treatment hasnt been determined. Blood tests may be needed to check for unwanted effects. Some that are rare (occurring in less than 10% of patients) are not listed here. Femara may not be right for you if you have certain medical conditions or other factors that affect your health. Is the ketogenic diet right for autoimmune conditions? Its possible that you may continue to have side effects from Femara even after you stop taking it. The half-life of Femara is about 2 days. Its available in one strength: 2.5 mg. For information on the effectiveness of Femara, see the Femara uses section below. Its used to treat the following types of cancer: Femara comes as a tablet you take by mouth once per day. To find out how often these side effects occurred in clinical studies, see the drugs prescribing information. If youre interested in using Femara for this purpose, talk with your doctor. Keep reading to learn more. Cancer cells multiply quickly, but some healthy cells in your body also multiply quickly. Serious side effects from Femara can occur, but they arent common. You might take a look at the Calling Long Term Survivors thread, I believe there's a couple of women who have been on it for 4+ years. You shouldnt use Femara while pregnant or breastfeeding. Femara is a kind of hormone therapy. Sharing this information can help you avoid potential interactions. If youre concerned about weight gain during your Femara treatment, talk with your doctor. However, if you think youre having a medical emergency, you should call 911 or your local emergency number. For details about how side effects for these drugs compare, see the Arimidex vs. letrozole section of this article. Some side effects, such as osteoporosis (weakened bones), will not get better on their own, even after you stop taking Femara. The usual dosage of Femara for inducing ovulation is 2.5 mg taken by mouth once daily for 5 days. Femara is prescribed to treat certain types of breast cancer in adult females* who have gone through menopause. If you think youre experiencing new or worsening depression or anxiety while taking Femara, talk with your doctor. Both Femara and clomiphene may be prescribed to treat female* infertility. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. No, Femara tablets should be swallowed whole. The lists below describe some of the more common side effects that Femara may cause. bone, muscle, or joint pain*. They can help determine if you should keep taking Femara or switch to a different treatment. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Early-stage breast cancer that has been treated with tamoxifen citrate for at least 5 years. https://www.drugs.com/pro/letrozole.html, Letrozole (Femara) Breast cancer now. Your bones rely on estrogen to keep them strong. Femara contains the active drug letrozole and is available as a generic drug called letrozole. But if they become bothersome, talk with your doctor or pharmacist. However, its possible that certain plant-based estrogens (called phytoestrogens) could make Femara less effective. These include: Youre more likely to have success with Femara treatment for infertility if your body isnt already ovulating. And your doctor can use this information to adjust your treatment plan if needed. Clomiphene is approved to treat infertility in females. These effects are called interactions. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. When will I ovulate after taking letrozole? reduces the risk of a new breast cancer . HR+ breast cancer is encouraged to grow by hormones, including estrogen. Use of the term male in this article refers to sex assigned at birth. Most people who use Femara take the drug for at least 5 years. Oftentimes women with PCOS dont ovulate as usual, so they have trouble becoming pregnant. Femara is approved to treat certain types of early and advanced breast cancer. Femara and clomiphene work in slightly different ways in your body to induce ovulation. Taking Femara in addition to having gone through menopause can weaken your bones even more. It should be safe to drink alcohol during your Femara treatment. As a type of hormone therapy, Femara works by lowering estrogen levels in your body. Arimidex (anastrozole) is a brand-name prescription drug thats used for certain types of breast cancer. If you have questions or concerns about using Femara for infertility, talk with your doctor. What Types of Breast Cancer Have the Highest Recurrence Rates? The types include: To learn more about these conditions and how Femara is used to treat them, see the What is Femara used for? section below. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If you have questions about how Femara may affect your bone density, talk with your doctor. breast and liver cancer in 2010. chemo and radio. Some people may have an allergic reaction to Femara. If you have liver problems, your doctor may recommend that you take one tablet every other day. This signals your pituitary gland to release hormones called follicle stimulating hormone (FSH) and luteinizing hormone (LH). So, chemotherapy can affect both healthy cells and cancer cells. Taking a Break From Letrozole Therapy After Breast Cancer. If your bones become weak during treatment, your doctor may prescribe medication for you to help strengthen your bones. Its a type of drug called an aromatase inhibitor. The following drugs should not be used while youre taking Femara: There arent any herbs or supplements that have been specifically reported to interact with Femara. After youve gone through menopause, your ovaries no longer produce estrogen. But both drugs are usually taken for 5 days at the start of your menstrual cycle. If youre concerned about how Femara might affect your cholesterol levels, talk with your doctor. Taking Femara can cause high cholesterol in some people. A CBC can help detect some blood cancers, but it cannot detect breast cancer. However, this particular treatment approach isnt right for everyone. Its meant to be taken as a long-term treatment. International guidelines recommend letrozole (the active drug in Femara) as an effective treatment for infertility. If you have trouble swallowing Femara tablets, talk with your doctor or pharmacist about ways to help make it easier for you to take your medication. Prophylactic mastectomy is surgery to remove breast tissue. You should keep taking Femara for as long as your doctor recommends. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Different interactions can cause different effects. Letrozole works by decreasing the amounts of these hormones in the body. When you take the drug, it stops androgens in your body from converting into estrogen. * Its mainly used when infertility is caused by problems with ovulation (the release of eggs from your ovaries). Here are answers to some frequently asked questions about Femara. By stopping aromatase from working, Femara lowers the amount of estrogen in your body. Both Femara and Arimidex belong to a group of drugs called aromatase inhibitors. These include: Note: For more information about the potential negative effects of Femara, see the Femara side effects section above. You can also visit the Femara manufacturers website to see if there are support options. But sometimes the drug is used off-label in people with this condition. With advanced breast cancer, the cancer has spread to nearby areas or lymph nodes (called locally advanced breast cancer), or it has spread to other parts of the body (called metastatic breast cancer). Its not chemotherapy, which is a type of cancer drug that most commonly causes hair loss. Below are commonly used dosages, but always take the dosage your doctor prescribes. Chemotherapy describes traditional drugs used to treat cancer. Learn more. This date is typically 1 year from the date they dispensed the medication. Talk with your doctor about your health history before you take Femara. Many drugs are available to treat infertility. Maintaining a moderate weight. Femara stays in your body for about 10 days after you stop taking the drug. Breast cancer cells may form a tumor in the breast and spread to other areas of the body. In addition, drugs and other products that contain estrogen, such as vaginal creams, may decrease the effects of Femara. Femara can interact with several types of drugs. Femara isnt currently approved to treat infertility in females. Precautions. Am I at a higher risk for certain side effects from Femara? If your doctor thinks Femara has stopped working for you, talk with them about whether stopping treatment could be beneficial for you. When you take Femara to induce (cause) ovulation, the drug is cleared from your body within several days after youve stopped taking it. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms. You should avoid drinking large amounts of alcohol while youre taking Femara. Swelling, another common side effect of Femara, can cause you to gain weight as your body holds on to water. If youre interested in finding an alternative to Femara, talk with your doctor. For information on how the drug performed in clinical studies, see Femaras prescribing information. If you have questions about the risks of Femara use in pregnancy, talk with your doctor. Here are a few other questions you may want to ask your doctor about Femara: In addition, you can learn about breast cancer and its treatment options by subscribing to Healthlines breast cancer newsletter. But you wont be able to notice it working in your body. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Femara is also used off-label to treat infertility. Femara contains the active drug letrozole, while Clomid contains the active drug clomiphene. Those that have been reported with Femara include: To learn more about each of these side effects, see Side effects explained below. You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. However, the drug may be used off-label for this purpose. And some may be easily managed, too. Your doctor will help you to weigh potential risks and benefits of taking Femara for a long period of time. Femara, which works by lowering your estrogen level, is prescribed for females* whove gone through menopause. Pay depends on your individual situation this helps prevent others, including estrogen often... Risks and benefits of taking Femara, talk with your doctor thinks Femara has stopped working for you if think... 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